Energy and Commerce Cures


A path to 21st century cures


In the 21st century, health care innovation is happening at lightning speed. From the mapping of the human genome to the rise of personalized medicines that are linked to advances in molecular medicine, we have seen constant breakthroughs that are changing the face of disease treatment, management, and cures. Health research is moving quickly, but the federal drug and device approval apparatus is in many ways the relic of another era. We have dedicated scientists and bold leaders at agencies like the NIH and the FDA, but when our laws don’t keep pace with innovation, we all lose.
If we want to save more lives and keep this country the leader in medical innovation, we have to make sure there’s not a major gap between the science of cures and the way we regulate these therapies.
That is why, for the first time ever, we in Congress are going to take a comprehensive look at what steps we can take to accelerate the pace of cures in America. We are looking at the full arc of this process – from the discovery of clues in basic science, to streamlining the drug and device development process, to unleashing the power of digital medicine and social media at the treatment delivery phase.
We know we don’t have all the answers. That’s why we’re asking questions first. We are listening.  We want to know how to close the gaps between advances in scientific knowledge about cures and the regulatory policies created to save more lives.

Over the next several months, members will take a comprehensive look at the full arc of this process - from the discovery to development to delivery - to determine what steps we can take to ensure we are taking full advantage of the advances this country has made in science and technology and use these resources to keep America as the innovation capital of the world.

WATCH Chairman Upton and Rep. Diana DeGette unveil the landmark initiative.


White Papers

21st Century Cures: A Call to Action (May 1, 2014)

21st Century Cures: An Update on the President's Council of Advisors on Science and Technology 2012 Report on Propelling Innovation (May 12, 2014)

21st Century Cures--Patients (May 16, 2014)

21st Century Cures: Digital Health Care (June 17, 2014)


21st Century Cures Roundtable (May 6, 2014)

21st Century Cures: The President's Council of Advisors on Science and Technology (PCAST) Report on Drug Innovation (May 20, 2014)

21st Century Cures: Examining the Role of Incentives in Advancing Treatments and Cures for Patients (June 11, 2014)

21st Century Cures Roundtable: Digital Health Care (June 24, 2014)

21st Century Cures: Modernizing Clinical Trials (July 9, 2014)

21st Century Cures: Incorporating the Patient Perspective (July 11, 2014) 

21st Century Technology for 21st Century Cures (July 17, 2014)

21st Century Cures: Examining Barriers to Ongoing Evidence Development and Communication (July 22, 2014)

21st Century Cures Roundtable on Personalized Medicine (July 23, 2014)


Wall Street Journal: Drug Companies Join NIH in Study of Alzheimer's, Diabetes, Rheumatoid Arthritis, Lupus (February 4, 2014)

U.S. News & World Report: Upton: Curing Disease With a Little Help From Our Friends (March 6, 2014)

Breitbart: Hope Comes to RHOB 2123: Fred Upton Leads a Cure Strategy for the 21st Century (May 9, 2014)

Holland Sentinel: Our View: Bring Drug Approval Process into the 21st Century (May 29, 2014)

Morning Consult: Life Sciences: A New Opportunity for Innovation (June 5, 2014)

Associated Press: New study aims to rapidly test lung cancer (June 17, 2014)

CQ Roll Call: House Energy & Commerce on the #Path2Cures (June 20, 2014)

Morning Consult: We Need 21st Century Clinical Trials to Produce 21st Century Cures (July 9, 2014)

BIOtechNow: Jim Greenwood talks 21st Century Cures with Chairman Fred Upton (July 16, 2014)

Press Releases

A Path to 21st Century Cures (April 30, 2014)

Roundtable and White Paper A Part of 21st Century Cures (May 1, 2014)

A Path to 21st Century Cures Also Creates a Path to a Stronger Economy (May 2, 2014)

Upton and DeGette Begin First Public Conversation About How to Accelerate the #Path2Cures (May 6, 2014)

What They're Saying on Social Media About Inagural 21st Century Cures Roundtable (May 9, 2014)

21st Century Cures Continues Seeking Feedback (May 12, 2014)

Latest White Paper Seeks Input from Patients and Advocates Regarding Gap Between Known Diseases and Available Treatmeants (May 16, 2014)

Health Subcommittee Examines How Incentives Can Be Used to Accelerate #Path2Cures (June 11, 2014)

21st Century Cures: Leveraging Technology to Accelerate the #Path2Cures (June 17, 2014)

Twitter Guide for Next Week's 21st Century Cures Roundtable - All Star Lineup Set for Digital Health Care Discussion (June 19, 2014)

Health Subcommittee Examines Opportunities to Modernize Clinical Trials (July 9, 2014)

FDA and Patient Groups Take Center Stage as Part of Effort to Accelerate #Path2Cures  (July 11, 2014)

Highlights from 21st Century Technology for 21st Century Cures Testimony (July 17, 2014)

Subcommittees Team Up to Learn How 21st Century Technology Can Improve 21st Century Cures (July 17, 2014)

21st Century Cures Roundtable on Personalized Medicine Scheduled for WEDNESDAY (July 18, 2014)

#Path2Cures Requires Collaboration and Transparency (July 22, 2014)

Third Roundtable Examines Personalized Medicine and the #Path2Cures (July 23, 2014) 

Connect with Us

The committee is seeking input on this bold new initiative from a wide variety of interested stakeholders.

Engage on social media by liking us on Facebook, Following us on Twitter, and using the hashtag #Path2Cures.

Email the committee using the email address

21st Century Cures is a truly collaborative effort. Please be advised that submissions sent to will be made publicly available on as part of the effort to encourage continued discussion about opportunities and ideas to accelerate the pace of cures. We thank you for participating.